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AMR from agriculture in the environment

Project Number # 3040

Significance of the environment as a reservoir for antimicrobial resistance from agricultural origin

Project #3040 is a pioneering research venture and cross-sectoral collaboration of water, environment, health and agriculture. The study collected data and baseline information about the microbial communities and types and amounts of AMR genes present in manure, as well as water and sediment from several rivers and waterbodies. To provide globally comparative data sets and to link this study directly to local epidemiological data, high-specificity real-time quantitative polymerase chain reaction (qPCR) assays were used.

This study provides further indication that the environment, humans and animals are intrinsically linked and underpins the importance of the need for multi-sector AMR stewardship and surveillance, and highlights that actions in one sector/area can potentially have impacts on the others.

Through these activities EPA will be able to assess whether ARB&G is a significant issue for EPA core business activities (environmental monitoring, discharge/waste disposal permitting and regulation) as well as determine targets for local data collection and surveillance.